Apthen are small, round or oval, open spots on the oral mucosa. The reason, why they are developing, is still unknown. But it seems they have the same action mechanisms like herpes – thus sun, stress, and mechanical stimuli. In opposite to herpes apthen are harmless, not infective – but very painful. For the treatment solutions are recommended – mainly chlorhexidine-containing – that are available in the pharmacy. Also ointments with disinfectant and wound healing enhancing effect that will be spotted directly to the inflamed spot using a clean cotton bud will provide a soothing, like e.g. Pyralvex®.